Xactagenttt has developed technology that makes reporter cells a powerful tool for understanding gene expression in biological research and drug discovery.

We accomplish this by inserting the reporter into endogenous genes.  This is important because our reporter cells retain complete gene regulation including normal promoters, enhancers, suppressors, and DNA methylation.  We have further engineered the mRNA to retain the normal 3’ and 5’ un-translated regions of the gene, so that mRNA stability and direct responses to siRNAs and micro-RNAs are retained.  Finally, we have engineered the vectors for the exceptional sensitivity required for high throughput screening (HTS).  Our reporter cells include known genes, predicted genes, and previously unidentified gene transcripts.

We provide reporter cells, libraries of reporter cells, assay reagents, and protocols for research use, as well as contract research and custom cell production for our customers.